关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗ACTN1/2/3/4多克隆抗体
英文名称: Anti-ACTN1/2/3/4 rabbit polyclonal antibody
别 名: BDPLT15/CMD1AA/FSGS; FSGS1; ACTININ-4
抗 原: ACTN1/2/3/4
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
反应种属: Human Mouse Rat
相关类别: 一抗
标记物: Unconjugate
克隆类型: Unconjugate
技术规格
Background: | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
Applications: | WB |
Name of antibody: | ACTN1/2/3/4 |
Immunogen: | Synthesized peptide derived from internal of human ACTN4. |
Full name: | actinin, alpha 1/2/3/4 |
Synonyms: | BDPLT15/CMD1AA/FSGS; FSGS1; ACTININ-4 |
SwissProt: | P12814/P35609/Q08043/O43707 |
WB Predicted band size: | 103/104/103/105 kDa |
WB Positive control: | 293 cells, Hela cells and A549 cells lysates |
WB Recommended dilution: | 500-3000 |