关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗CEND1多克隆抗体
英文名称:Anti-CEND1 rabbit polyclonal antibody
别 名: cell cycle exit and neuronal differentiation 1; BM88
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: CEND1
反应种属:Human, Mouse, Rat
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | BM88, also known as CEND1 (cell cycle exit and neuronal differentiation protein 1), is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A. |
Applications: | ELISA, IHC |
Name of antibody: | CEND1 |
Immunogen: | Synthetic peptide of human CEND1 |
Full name: | cell cycle exit and neuronal differentiation 1 |
Synonyms: | BM88 |
SwissProt: | Q8N111 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human liver cancer and human prostate cancer |
IHC Recommend dilution: | 25-100 |
新乡本地兔抗CEND1热销信息