关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称： 兔抗YTHDF1多克隆抗体
英文名称：Anti-YTHDF1 rabbit polyclonal antibody
别 名：YTH N6-adenosine RNA binding protein 1; C20orf21
相关类别：一抗
储 存：冷冻（-20℃）
宿 主：Rabbit
抗 原：YTHDF1
反应种属：Human, Mouse
标 记 物：Unconjugate
克隆类型：rabbit polyclonal
技术规格
Background: | YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. Specifically recognizes and binds N6-denosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440). |
Applications: | ELISA, IHC |
Name of antibody: | YTHDF1 |
Immunogen: | Synthetic peptide of human YTHDF1 |
Full name: | YTH N6-denosine RNA binding protein 1 |
Synonyms: | C20orf21 |
SwissProt: | Q9BYJ9 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human cervical cancer |
IHC Recommend dilution: | 40-200 |
