兔抗COX4I1多克隆抗体

Background:

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.

Applications:

ELISA, WB, IHC

Name of antibody:

COX4I1

Immunogen:

Synthetic peptide of human COX4I1

Full name:

cytochrome c oxidase subunit IV isoform 1

Synonyms:

COX4; COXIV; COX4-1

SwissProt:

P13073

IHC positive control:

Human tonsil and human prostate cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

20 kDa

WB Positive control:

NIH/3T3,Hela and 293T cell lysates

WB Recommended dilution:

500-2000