关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗BRCA1 (Phospho-Ser1423)多克隆抗体
英文名称:Anti-BRCA1 (Phospho-Ser1423) rabbit polyclonal antibody
别 名: IRIS; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; PPP1R53
相关类别:一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: BRCA1 (Phospho-Ser1423)
反应种属:Human
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation |
Applications: | WB, IHC |
Name of antibody: | BRCA1 (Phospho-Ser1423) |
Immunogen: | Synthetic peptide of human BRCA1 (Phospho-Ser1423) |
Full name: | breast cancer 1, early onset (Phospho-Ser1423) |
Synonyms: | IRIS; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; PPP1R53 |
SwissProt: | P38398 |
IHC positive control: | Human breast carcinoma |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 208 kDa |
WB Positive control: | HT29 cells untreated or treated with Anisomycin |
WB Recommended dilution: | 500-1000 |
主营行业:试剂盒 |
公司主营:elisa试剂盒,检测试剂盒,酶联检测试剂盒厂家,试剂盒批发--> |
主营地区:上海 |
企业类型:有限责任公司 |
公司成立时间:2010-01-01 |
员工人数:5 - 10 人 |
研发部门人数:5 - 10 人 |
经营模式:生产+贸易型 |
经营期限:1949-01-01 至 2031-01-01 |
最近年检时间:2020年 |
年营业额:人民币 10 万元/年以下 |
年出口额:人民币 10 万元/年以下 |
年进口额:人民币 10 万元/年以下 |
是否提供OEM:是 |
公司邮编:201500 |
公司电话:021-54845833 |
公司邮箱:2881498548@qq.com |
公司网站:http://www.tw-reagent.com |