关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称： 兔抗IGF1R(Phospho-Tyr1161) 多克隆抗体
英文名称：Anti-IGF1R(Phospho-Tyr1161) rabbit polyclonal antibody
别 名： IGFR; CD221; IGFIR; JTK13
相关类别：一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： IGF1R(Phospho-Tyr1161)
反应种属：Human Mouse Rat
标 记 物：Unconjugate
克隆类型：Unconjugate
技术规格
Background: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Applications: | WB, IHC, IF |
Name of antibody: | IGF1R(Phospho-Tyr1161) |
Immunogen: | Peptide sequence around phosphorylation site of tyrosine 1161(D-I-Y(p)-E-T)derived from Human IGF-1R. |
Full name: | insulin-like growth factor 1 receptor |
Synonyms： | IGFR; CD221; IGFIR; JTK13 |
SwissProt: | P08069 |
IHC positive control: | Human breast carcinoma tissue |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 155 kDa |
WB Positive control: | 293 cells lysates untreated or treated with insulin |
WB Recommended dilution: | 500-1000 |
IF positive control: | MCF7 cells |
IF Recommend dilution: | 100-200 |
