关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称:兔抗UPF1多克隆抗体
英文名称:Anti-UPF1 rabbit polyclonal antibody
别 名: HUPF1; NORF1; RENT1; smg-2; pNORF1
相关类别:一抗
储 存: 冷冻(-20℃)
抗 原: UPF1
宿 主: Rabbit
反应种属:Human, Mouse
标记物: Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
Applications: | ELISA, WB, IHC |
Name of antibody: | UPF1 |
Immunogen: | Synthetic peptide of human UPF1 |
Full name: | UPF1 RNA helicase and ATPase |
Synonyms: | HUPF1; NORF1; RENT1; smg-2; pNORF1 |
SwissProt: | Q92900 |
ELISA Recommended dilution: | 1000-5000 |
IHC positive control: | Human liver cancer and Human thyroid cancer |
IHC Recommend dilution: | 50-200 |
WB Predicted band size: | 124 kDa |
WB Positive control: | Raji cells |
WB Recommended dilution: | 200-1000 |
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