关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗A多克隆抗体
英文名称: Anti-A rabbit polyclonal antibody
别 名: DOG1; TAOS2; ORAOV2; TMEM16A
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: A
反应种属: Human, Mouse
标 记 物: Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | TMEM16A, also known as DOG1, ORAOV2, TAOS2 or A (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events. |
Applications: | ELISA, WB, IHC |
Name of antibody: | A |
Immunogen: | Synthetic peptide of human A |
Full name: | anoctamin 1, calcium activated chloride channel |
Synonyms: | DOG1; TAOS2; ORAOV2; TMEM16A |
SwissProt: | Q5XXA6 |
ELISA Recommended dilution: | 1000-2000 |
IHC positive control: | Human thyroid cancer |
IHC Recommend dilution: | 25-100 |
WB Predicted band size: | 114 kDa |
WB Positive control: | Human fetal brain tissue |
WB Recommended dilution: | 200-1000 |