兔抗ATF4(Phospho-Ser219)多克隆抗体

Background:

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]

Applications:

WB

Name of antibody:

ATF4(Phospho-Ser219)

Immunogen:

Peptide sequence around phosphorylation site of Serine 219 (N-D-S(p)-G-T) derived from Human ATF-4.

Full name:

activating transcription factor 4

Synonyms：

CREB2; TXREB; CREB-2; TAXREB67

SwissProt:

P18848

WB Predicted band size:

39 kDa

WB Positive control:

COLO cells lysates

WB Recommended dilution:

500-1000