关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗KIR2DL1多克隆抗体
英文名称:Anti-KIR2DL1 rabbit polyclonal antibody
别 名:NKAT; NKAT1; p58.1; CD158A; KIR221; KIR-K64
相关类别:一抗
储 存:冷冻(-20℃) 避光
宿 主:Rabbit
抗 原:KIR2DL1
反应种属:Human
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. |
Applications: | WB |
Name of antibody: | KIR2DL1 |
Immunogen: | Fusion protein of human KIR2DL1 |
Full name: | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
Synonyms: | NKAT; NKAT1; p58.1; CD158A; KIR221; KIR-K64 |
SwissProt: | P43626 |
WB Predicted band size: | 39 kDa |
WB Positive control: | HepG2 cells |
WB Recommended dilution: | 500-2000 |
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廊坊本地兔抗KIR2D热销信息