关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗NUAK1多克隆抗体
英文名称:Anti-NUAK1 rabbit polyclonal antibody
别 名: ARK5
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: NUAK1
反应种属:Human, Mouse
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | NUAK family SNF1-like kinase 1 also known as AMPK-related protein kinase 5 (ARK5) is an enzyme that in humans is encoded by the NUAK1 gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. |
Applications: | ELISA, IHC |
Name of antibody: | NUAK1 |
Immunogen: | Synthetic peptide of human NUAK1 |
Full name: | NUAK family, SNF1-like kinase, 1 |
Synonyms: | ARK5 |
SwissProt: | O60285 |
ELISA Recommended dilution: | 2000-10000 |
IHC positive control: | Human lung cancer and Human liver cancer |
IHC Recommend dilution: | 100-300 |
上海通蔚实业有限公司位于中国率先大城市——中华人民共和国直辖市之一的上海,且依托上海张江高科生物研究优势,主要是一家经营elisa试剂盒、检测试剂盒、酶联检测试剂盒等产品的厂家,目前已发展成集科研、生产、销售为一体的创新性企业。
鹤壁本地兔抗NUAK1热销信息