关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称:兔抗PDHA1多克隆抗体
英文名称:Anti-PDHA1 rabbit polyclonal antibody
别 名: pyruvate dehydrogenase E1 alpha 1 subunit; PDHA; PDHAD; PHE1A; PDHCE1A
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: PDHA1
反应种属:Human, Mouse, Rat
标记物: Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: | ELISA, WB, IHC |
Name of antibody: | PDHA1 |
Immunogen: | Fusion protein of human PDHA1 |
Full name: | pyruvate dehydrogenase E1 alpha 1 subunit |
Synonyms: | PDHA; PDHAD; PHE1A; PDHCE1A |
SwissProt: | P08559 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human cervical cancer and Human tonsil |
IHC Recommend dilution: | 50-300 |
WB Predicted band size: | 43 kDa |
WB Positive control: | Mouse brain tissue, HepG2, Hela, A549 cell, Mouse skeletal muscle tissue, NIH/3T3 cell lysates |
WB Recommended dilution: | 1000-5000 |
德州本地兔抗PDHA1热销信息