关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称： 兔抗RIOX1多克隆抗体
英文名称：Anti-RIOX1 rabbit polyclonal antibody
别 名：ribosomal oxygenase 1; ROX; NO66; JMJD9; MAPJD; UR
相关类别：一抗
储 存：冷冻（-20℃）
宿 主：Rabbit
抗 原：RIOX1
反应种属：Human, Mouse, Rat
标 记 物：Unconjugate
克隆类型：rabbit polyclonal
技术规格
Background: | Oxygenase that can act as both a histone lysine delase and a ribosomal histidine hydroxylase. Specifically delates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially deates triated H3 'Lys-4' (H3K4me3) and monoated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for diated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by deating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation. |
Applications: | ELISA, IHC |
Name of antibody: | RIOX1 |
Immunogen: | Synthetic peptide of human RIOX1 |
Full name: | ribosomal oxygenase 1 |
Synonyms: | ROX; NO66; JMJD9; MAPJD; URLC2; hsNO66; C14orf169 |
SwissProt: | Q9H6W3 |
IHC positive control: | Human thyroid cancer and Human ovarian cancer |
IHC Recommend dilution: | 30-150 |
