兔抗CLDN7(Phospho-Tyr210)多克隆抗体

Background:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]

Applications:

WB

Name of antibody:

CLDN7(Phospho-Tyr210)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 210 (S-K-E-Y(p)-V) derived from Human Claudin 7.

Full name:

claudin 7

Synonyms：

CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1

SwissProt:

O95471

WB Predicted band size:

22 kDa

WB Positive control:

NIH/3T3 cells lysates

WB Recommended dilution:

500-1000