关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称：兔抗PPP4R2多克隆抗体
英文名称：Anti-PPP4R2 rabbit polyclonal antibody
别 名： PP4R2
相关类别：一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： PPP4R2
反应种属：Human Mouse
标记物： Unconjugate
克隆类型：Unconjugate
技术规格
Background: | Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair. |
Applications: | WB |
Name of antibody: | PPP4R2 |
Immunogen: | Synthesized peptide derived from internal of human PP4R2. |
Full name: | protein phosphatase 4, regulatory subunit 2 |
Synonyms： | PP4R2 |
SwissProt: | Q9NY27 |
WB Predicted band size: | 47 kDa |
WB Positive control: | K562 cells and COS7 cells lysates |
WB Recommended dilution: | 500-3000 |
上海通蔚实业有限公司位于中国率先大城市——中华人民共和国直辖市之一的上海，且依托上海张江高科生物研究优势，主要是一家经营elisa试剂盒、检测试剂盒、酶联检测试剂盒等产品的厂家，目前已发展成集科研、生产、销售为一体的创新性企业。
南充本地兔抗PPP4R2热销信息
