关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称： 兔抗INAVA多克隆抗体
英文名称：Anti-INAVA rabbit polyclonal antibody
别 名： innate immunity activator; C1orf106
相关类别：一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： INAVA
反应种属：Human, Mouse
标 记 物：Unconjugate
克隆类型：rabbit polyclonal
技术规格
Background: | Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance. Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion (PubMed:28436939). In the intestine, regulates adherens junction stability by regulating the degradation of CYTH1 and CYTH2, probably acting as substrate cofactor for SCF E3 ubiquitin-protein ligase complexes. Stabilizes adherens junctions by limiting CYTH1-dependent ARF6 activation (PubMed:29420262). |
Applications: | ELISA, IHC |
Name of antibody: | INAVA |
Immunogen: | Fusion protein of human INAVA |
Full name: | innate immunity activator |
Synonyms: | C1orf106 |
SwissProt: | Q3KP66 |
IHC positive control: | Human liver cancer |
IHC Recommend dilution: | 50-300 |
上海通蔚实业有限公司位于中国率先大城市——中华人民共和国直辖市之一的上海，且依托上海张江高科生物研究优势，主要是一家经营elisa试剂盒、检测试剂盒、酶联检测试剂盒等产品的厂家，目前已发展成集科研、生产、销售为一体的创新性企业。
淄博本地兔抗INAVA热销信息
